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008			080910s2005 nyua | 000 0 eng
020			_a019852563X (alk. paper)
020			_a0198568533 (alk. paper)
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050	0	0	_aRC268.5 _b.K56 2005
082	0	0	_a616.99/4071 _222
100	1		_aKnowles, Margaret A. _937566
245	1	0	_aIntroduction to the cellular and molecular biology of cancer / _cMargaret A. Knowles, Peter J. Selby.
260			_aNew York : _bOxford University Press, _c2005.
300			_axvii, 532 p. : _bill. ; _c25 cm.
500			_a"Oxford bioscience"--Cover.
505			_a1. What is cancer?; 2. The causes of cancer; 3. Inherited susceptibility to cancer; 4. DNA repair and cancer; 5. Epigenetic events in cancer; 6. Molecular cytogenetics of cancer; 7. Oncogenes; 8. Tumour suppressor genes; 9. The cancer cell cycle; 10. Cellular immortalization and telomerase activation in cancer; 11. Growth factors and their signalling pathways in cancer; 12. Apoptosis: molecular physiology and significance for cancer therapeutics; 13. Mechanisms of viral carcinogenesis; 14. Cytokines and cancer; 15. Hormones and cancer; 16. The spread of tumours; 17. Angiogenesis; 18. Stem cells, heamopoiesis, and leukaemia; 19. Animal models of cancer; 20. The immunology of cancer; 21. The molecular pathology of cancer; 22. From transcriptome to proteome; 23. Local treatment of cancer; 24. Chemotherapy; 25. Radiotherapy and molecular radiotherapy; 26. Monoclonal antibodies and therapy; 27. Immunotherapy of cancer; 28. Cancer gene therapy; 29. Screening; 30. Conclusions and prospects
520			_aThis new edition of Introduction to the Cellular and Molecular Biology of Cancer provides a comprehensive overview of cancer biology, covering the current status of both research and treatment. For the student or new researcher the breadth of cancer research can appear daunting, yet a broad understanding is essential for translation of laboratory findings into the clinic. Within the broad scope of the book, each topic is reviewed authoritatively by experts in the field, and the accompanying bibliographies allow rapid access to the relevant current literature. The book covers topics extending from the molecular alterations found in cancer cells and their causes to the current range of approaches to treatment. Since the publication of the previous edition in 1997 there has been unprecedented progress in cancer research: this is reflected by an extensive revision of all the material, and the addition of eight new chapters, covering DNA repair, epigenetic events, the cell cycle, cell immortalisation, apoptosis, angiogenesis, animal models, the genome, transcriptome and proteome, radiotherapy and molecular radiotherapy, immunotherapy, and gene therapy. The fourth edition of this popular book will serve as a text for both undergraduate and postgraduate use and also as an introduction for clinicians and scientists new to the field.
650		0	_aCancer _xMolecular aspects. _937567
650		0	_aCancer cells. _937568
700	1		_aSelby, P. _q(Peter) _937569
856	4		_3Table of contents only _uhttp://www.loc.gov/catdir/toc/ecip055/2004030576.html
856	4		_3Publisher description _uhttp://www.loc.gov/catdir/enhancements/fy0638/2004030576-d.html
856	4		_3Contributor biographical information _uhttp://www.loc.gov/catdir/enhancements/fy0725/2004030576-b.html
942			_2lcc _n0 _cBK
999			_c16658 _d16658